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      1. 該基因編碼一種蛋白質,其氨基端含有一個dexh盒,羧基端含有一個RNA基序。編碼蛋白作為一種核糖核酸酶發揮作用,由RNA干擾和小時態RNA(strna)途徑產生抑制基因表達的活性小RNA成分。選擇性剪接導致多個轉錄變體。
        This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

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          腫瘤基因檢測
        基因名:DICER1
        別名:DCR1,Dicer,Dicer1e,HERNA,K12H4.8-LIKE,MNG1,RMSE2
        基因ID:23405
        Chromosome:
        (GRCh37)
        14 Start: 95552565 End: 95624347 Strand: -1
        信號通路: DNA修飾及其它 
        登錄 后查看 DICER1基因突變 詳細信息。
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